Berks Catholic swept Brandywine Heights in Mertztown, 3-0, on Wednesday night for the second time this season.
Devon Merritt had another big game for the Saints (12-0, 13-1), tallying 15 kills. Courtney Wensel added 13 kills while Olivia Blankenbiller dished out 30 assists.
The Bullets (8-3, 8-3), celebrating senior night, were paced by 10 kills from Heather Swann.
Berks Catholic will enter the county tournament next week as the co-favorite with Exeter.