Brandywine Heights held a one-point lead at halftime, but could contain Hamburg in the second half.
The Lady Hawks outscored the Lady Bullets 31-20 in the final two quarters to capture a 56-46 victory on Thursday evening.
Sydney Lesher recorded a game-high 22 points for Hamburg. Kassidy Lesher added 16 points.
Brandywine's Deanna Daddona scored 18 points to lead the Bullets.